Liver and Renal Injury with Remdesivir treatment in SARS-CoV-2 Patients
| Autor: | null Rabiah Sadaf, Faiza Sadaqat Ali, Tazeen Rasheed, null Bader Faiyaz Zuberi |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Pakistan Journal of Medical Sciences. 39 |
| ISSN: | 1681-715X 1682-024X |
| Popis: | Objective: To determine the effect of Remdesivir on liver enzymes and renal functions in SARS-CoV-2 patients. Methods: This prospective cohort study was conducted at Dr. Ruth KM Pfau, Civil Hospital Karachi between 1st December 2021 to 31st January, 2022. All patients of severe SARS-CoV-2 infection who received Inj. Remdesivir for five days as per protocol of SARS-CoV-2 management were included. Biodata of selected patients including age, gender, diabetic, hypertensive status was recorded. Patients Liver Function Tests and Serum Creatinine were performed on days 0, 3, 5, 7 and 14. Results: This study included 85 patients, out of which 55 (64.7%) were males and 30 (35.3%) were females. Out of 85 patients, Remdesivir was stopped in 3 (3.5%) patients. Among these three patients Remdesivir was stopped in one patient on day three because of decrease in CrCl to |
| Databáze: | OpenAIRE |
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