Analysis of the possible involvement of the glutamate transporter gene EAAT2 and the glutamate receptor genes GRIA1 and GRIA2 in the pathogenesis of motor neuron disease in the Russian population

Autor: Skvortsova Vi, Alekhin Av, Slominskiĭ Pa, M. I. Shadrina, Levitskiĭ Gn, Semenova Ev, Zherebtsova Al, Limborskaia Sa
Rok vydání: 2006
Předmět:
Zdroj: Russian Journal of Genetics. 42:89-93
ISSN: 1608-3369
1022-7954
DOI: 10.1134/s1022795406010133
Popis: Polymorphisms of the genes of the glutamatergic system EAAT2, GRIA1, and GRIA2 have been analyzed in patients with sporadic motor neuron disease (MND) from Russia. The disease is not associated with polymorphic alleles of the genes studied, which indicates that EAAT2, GRIA1, and GRIA2 play an insignificant role in the pathogenesis of sporadic MND.
Databáze: OpenAIRE