α-d-Glucofuranose and α-d-allofuranose diacetonides and silyl ether of α-d-glucofuranose diacetonide in dithiophosphorylation reactions

Autor: Ilnar D. Nizamov, Il'yas S. Nizamov, Elvira S. Batyeva, Alexandra D. Voloshina, R. A. Cherkasov, Timur G. Belov, Yevgeniy N. Nikitin
Rok vydání: 2016
Předmět:
Zdroj: Heteroatom Chemistry. 27:345-352
ISSN: 1042-7163
DOI: 10.1002/hc.21344
Popis: α-d-Glucofuranose and α-d-allofuranose diacetonides react with 2,4-diorganyl 1,3,2,4-dithiadiphosphetane-2,4-disulfides to form optically active dithiophosphonates in 78–81% yields, which are transformed into the corresponding ammonium salts in 90–97% yields by the treatment of n-hexadecylamine. The S-silyldithiophosphonate was prepared in 93% yield by the reaction of 2,4-bis(butoxyphenyl) 1,3,2,4-dithiadiphosphetane-2,4-disulfide with silyl ether of α-d-glucofuranose diacetonide. One of the salts obtained possesses antibacterial activity against Staphylococcus aureus ATCC 6538-P.
Databáze: OpenAIRE