Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients

Autor: Qiang Meng, Yong Liu, Yutao Ren, Hao Wu, Jiale Zhang, Huanfa Li, Shan Dong, Jiangpeng Jing, Xiaofang Liu, Changwang Du, Hua Zhang
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-2339934/v1
Popis: The predictors of long-term seizure outcomes after resectivesurgery for focal epilepsy, for an update on the features of good and poor outcomes is investigated. A retrospective study of patients with focal epilepsy undergoing resectivesurgery from March 2011 toApril 2019 was performed. There were 3 groups according to the seizure outcomes: group A, seizure freedom; group B, seizure improvement; group C, no improvement. Five comparisons were performed: comparison 1, A vs. B and C; comparison 2, A vs. B; comparison 3, A vs. C; comparison 4, B vs. C; comparison 5, A and B vs. C. Predictors of seizure outcomes were identified by multivariate logistic regression analysis. Of all 833 patients, 561 (67.3%) patients remained seizure-free at the last follow-up, 203 (24.4%) patients had seizure improvement, and 69 (8.3%) had no improvement. The mean follow-up duration was 5.2 years (range: 2.7 to 9.6). Predictors of better outcomes included epilepsyduration
Databáze: OpenAIRE