The microdetermination of salicylic acid and certain derivatives

Autor:	M.Z. Barakat, Shaker Talkhan El Aassar, Ahmed Shawki Fayzalla
Rok vydání:	1970
Předmět:	Hydrolysis chemistry.chemical_compound Chromatography Chemistry Potassium bromide Biological fluids Organic chemistry Bromosuccinimide Sulfuric acid Spectroscopy Salicylic acid Analytical Chemistry
Zdroj:	Microchemical Journal. 15:10-24
ISSN:	0026-265X
DOI:	10.1016/0026-265x(70)90155-4
Popis:	A new titrimetric method for the microdetermination of salicylic acid or certain derivatives is described. The proposed method is based on the fact that N -bromosuccinimide in the presence of dilute sulfuric acid and potassium bromide readily brominates salicylic acid and certain derivatives after hydrolysis. The mechanism of the reaction is discussed. The proposed method is simple, rapid, and sufficiently accurate to determine concentrations as low as 100 μg of salicylic acid or certain derivatives. The experimental error does not exceed ±2%. The method was also used for the determination of salicylic acid in such biological fluids as blood or urine with an error not exceeding ±10%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7980606d8d0e436f8e29b9c81861e856 https://doi.org/10.1016/0026-265x(70)90155-4 Zobrazit plný text záznamu