Monoclonal antibodies reactive with B-lymphocytes and histiocytes in paraffin sections

Autor:	Robert J. Lukes, Barbara Felder, Alan L. Epstein, Elimelech Okon, Clive R. Taylor
Rok vydání:	1985
Předmět:	Cancer Research Pathology medicine.medical_specialty Immunoperoxidase medicine.drug_class Biology Monoclonal antibody Lymphatic system Oncology immune system diseases hemic and lymphatic diseases medicine biology.protein Immunohistochemistry Lymph Antibody Immunostaining Histiocyte
Zdroj:	Cancer. 56:95-104
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19850701)56:1<95::aid-cncr2820560116>3.0.co;2-k
Popis:	Representative sections of normal lymph nodes, cases of reactive lymphadenopathy, and Hodgkin's disease were examined using two monoclonal antibodies reactive in paraffin sections using an immunoperoxidase technique. Antibody LN-1 recognizes B-lymphocytes in follicles; antibody LN-2 recognizes a broader spectrum of B-cells, and also shows positivity with some monocytes/histiocytes. The pattern of immunostaining with these antibodies is described with particular reference to Hodgkin The pattern of immunostaining with these antibodies is described with particular reference to Hodgkin and Reed-Sternberg cells. Some of the implications are discussed.
Databáze:	OpenAIRE
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