Multisystemic Inflammatory Syndrome Temporally Associated with COVID-19 in a Regional Pediatric Hospital from México

Autor: Joel Barroso-Santos, Angelina Ingrid Robledo-Martínez, Sara Elva Espinosa-Padilla, Rubén Genaro Hurtado del Ángel, Felipe Arteaga-García, Mónica Langarica-Bulos, José Antonio Madrid-Gómez-Tagle, Beatriz Adriana Sánchez-Reyes, Sarai Eunice Hernández-Cadena, Jorge Iván Suárez-Soto, Carolina Delgado-Amézquita, Brenda Godínez-Hernández, Octavio Otamendi-Canales, Angélica Saraí Jiménez-Osorio
Rok vydání: 2023
Předmět:
Zdroj: Pediatric Reports. 15:341-348
ISSN: 2036-7503
DOI: 10.3390/pediatric15020030
Popis: Multisystemic inflammatory syndrome (MIS-C) is an inflammatory condition temporally associated with COVID-19 in children; nevertheless, the clinical and immunologic spectrum of MIS-C is heterogeneous, and its long-term effects are unknown. During the period of August 2020 to December 2021, a total of 52 MIS-C cases were confirmed in pediatric patients from the Hospital del Niño DIF Hidalgo, diagnosed using criteria from the World Health Organization. All patients had serologic IgG confirmation of SARS-CoV2, the mean age of the patients was 7 years, and 94% of the patients did not have a previous underlying disease. In addition to the presentation of lymphopenia, neutropenia, and thrombocytopenia, elevations in D-dimer and ferritin levels were observed in all patients. There was clinical improvement with intravenous gamma globulin and corticosteroid treatment.
Databáze: OpenAIRE
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