Simplified scintigraphic methods for measuring gastrointestinal transit times
Autor: | Jesper Graff, Jan L. Madsen, K Brinch |
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Rok vydání: | 2000 |
Předmět: |
medicine.medical_specialty
Meal medicine.diagnostic_test Gastric emptying Physiology Chemistry Stomach digestive oral and skin physiology chemistry.chemical_element Scintigraphy Technetium Gastroenterology digestive system diseases Small intestine medicine.anatomical_structure Internal medicine medicine Ingestion Digestion |
Zdroj: | Clinical Physiology. 20:262-266 |
ISSN: | 0144-5979 |
DOI: | 10.1046/j.1365-2281.2000.00256.x |
Popis: | To investigate whether simple transit measurements based on scintigraphy performed only 0, 2, 4 and 24 h after intake of a radiolabelled meal can be used to predict the mean transit time values for the stomach, the small intestine, and the colon, a study was conducted in 16 healthy volunteers. After ingestion of a meal containing 111indium-labelled water and 99mtechnetium-labelled omelette, imaging was performed at intervals of 30 min until all radioactivity was located in the colon and henceforth at intervals of 24 h until all radioactivity had cleared from the colon. Gastric, small intestinal and colonic mean transit times were calculated for both markers and compared with fractional gastric emptying at 2 h, fractional colonic filling at 4 h, and geometric centre of colonic content at 24 h, respectively. Highly significant correlations were found between gastric mean transit time and fractional gastric emptying at 2 h (111In: r=0.95, P |
Databáze: | OpenAIRE |
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