Simplified scintigraphic methods for measuring gastrointestinal transit times

Autor: Jesper Graff, Jan L. Madsen, K Brinch
Rok vydání: 2000
Předmět:
Zdroj: Clinical Physiology. 20:262-266
ISSN: 0144-5979
DOI: 10.1046/j.1365-2281.2000.00256.x
Popis: To investigate whether simple transit measurements based on scintigraphy performed only 0, 2, 4 and 24 h after intake of a radiolabelled meal can be used to predict the mean transit time values for the stomach, the small intestine, and the colon, a study was conducted in 16 healthy volunteers. After ingestion of a meal containing 111indium-labelled water and 99mtechnetium-labelled omelette, imaging was performed at intervals of 30 min until all radioactivity was located in the colon and henceforth at intervals of 24 h until all radioactivity had cleared from the colon. Gastric, small intestinal and colonic mean transit times were calculated for both markers and compared with fractional gastric emptying at 2 h, fractional colonic filling at 4 h, and geometric centre of colonic content at 24 h, respectively. Highly significant correlations were found between gastric mean transit time and fractional gastric emptying at 2 h (111In: r=0.95, P
Databáze: OpenAIRE