Arterial and Cerebral Venous Blood Gases Differ in Acute Tension Pneumothorax

Autor: J. Peter Harris, Arthur E. Kopelman, Donald Holbert, Thomas M. Louis
Rok vydání: 1993
Předmět:
Zdroj: Journal of Maternal-Fetal and Neonatal Medicine. 2:63-69
ISSN: 1476-4954
1476-7058
DOI: 10.3109/14767059309017228
Popis: Tension pneumothorax (TP) complicates the course of respiratory distress syndrome in about 13% of low birth weight infants. If TP is accompanied by hypotension the majority of infants will develop large intraventricular hemorrhages or cerebral ischemic lesions. Severe TP likely produces cerebral ischemia as a consequence of systemic hypotension, but in a previous clinical study we did not demonstrate accompanying abnormalities in the arterial blood gases. Because of the possibility that arterial blood gases do not reflect tissue acid-base abnormalities during TP, this study was designed to compare sagittal sinus blood gases with arterial gases during and following recovery from severe TP in 5-7 day piglets.During a 4 minute TP mean blood pressure and common carotid blood flow dropped by 75% and 73%, respectively, and the electroencephalogram became isoelectric. Also sagittal sinus pCO2 rose (from 45.7 to 63.4 mmHg, P < 0.02) and pH fell (from 7.31 to 7.23, P < 0.02). During TP, end-tidal CO2 decreased (fr...
Databáze: OpenAIRE