Gastrointestinal side effects of iron supplements: potential effects on gut microbiota

Autor: E. A. Balashova, I. L. Shadrina, A. A. Pogodina
Rok vydání: 2022
Předmět:
Zdroj: Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 67:18-26
ISSN: 2500-2228
1027-4065
Popis: Iron deficiency anemia remains a significant problem in pediatric practice with its prevalence of 6–40% in the Russian Federation. Oral iron supplementation is the most common first-line treatment especially in outpatient setting. Despite adequate efficacy of oral supplementation, the problem of its side effects and, primarily, gastrointestinal toxicity remains. This review examines the issue of the potential effect of iron supplementation on gut microbiota composition, presents data from studies in animal models and in clinical studies.
Databáze: OpenAIRE