Adapting adaptive design methods to accelerate adoption of a digital asthma management intervention
| Autor: | Bruce G Bender, Peter J Cvietusa, Glenn K Goodrich, Diane K King, Jo Ann Shoup |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Translational Behavioral Medicine. 13:149-155 |
| ISSN: | 1613-9860 1869-6716 |
| DOI: | 10.1093/tbm/ibac093 |
| Popis: | Investigators conducting translational research in real-world settings may experience changes that create challenges to the successful completion of the trial as well as post-trial adoption and implementation. Adaptive designs support translational research by systematically adapting content and methods to meet the needs of target populations, settings and contexts. This manuscript describes an adaptive implementation research model that provides strategies for changing content, delivery processes, and research methods to correct course when anticipated and unanticipated circumstances occur during a pragmatic trial. The Breathewell Program included two large pragmatic trials of the effectiveness of a digital communication technology intervention to improve symptom management and medication adherence in asthma care. The first trial targeted parents of children with asthma; the second targeted adults with asthma. Adaptations were made iteratively to adjust to dynamic conditions within the healthcare setting, informed by prospectively collected stakeholder input, and were categorized retrospectively by the authors as proactive or reactive. Study outcomes demonstrated improved treatment adherence and clinical efficiency. Kaiser Permanente Colorado, the setting for both studies, adopted the speech recognition intervention into routine care, however, both interventions required numerous adaptations, including changes to target population, intervention content, and internal workflows. Proactive and reactive adaptations assured that both trials were successfully completed. Adaptive research designs will continue to provide an important pathway to move healthcare delivery research into practice while conducting ongoing effectiveness evaluation. |
| Databáze: | OpenAIRE |
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