Estimation of intrapartum serum vitamin D levels of mother and newborn and its association with newborn anthropometric indices in a tertiary care teaching hospital in Eastern India: An observational study

Autor: Rubina Saha, Pragya Kumar, Shamshad Ahmad, Mala Mahto, Monika Anant, Alok Ranjan, Anantha Padmanabhan A
Rok vydání: 2023
DOI: 10.21203/rs.3.rs-2695741/v1
Popis: Background Maternal vitamin D deficiency during pregnancy is a common issue and a significant public health problem at the global level. Foetal growth and development has been over the years studied and it was discovered that it has some linkage with Vitamin D. Aim & Objective To estimate vitamin D level of mothers and neonate and find association between serum vitamin D status of mothers and neonate anthropometry. Materials and Methods The research was carried out between January 2020 and April 2021. A total of 97 participants—singleton (mother and neonate pair) at the time of delivery—were enrolled using convenient sampling. Five millilitres each of cord blood and maternal venous blood were taken at the time of delivery. Chemiluminescent immunoassay was used to analyse the vitamin D levels. One researcher measured the birth weight, length, head circumference, and chest circumference. Results- Mothers had 87.6% vitamin D deficiency, 5.2% insufficiency and 7.2% sufficiency. About 50.5% of new-borns were vitamin D deficient, 44.3% had insufficient vitamin D levels, and 5.2% had adequate vitamin D levels. Conclusion Insufficient vitamin D was reported in 92.8% of mothers. Neonatal vitamin D insufficiency was found to be in 94.8%. Neonatal vitamin D levels were substantially correlated with those of their mothers. Antenatal supplements of calcium along with vitamin D had seen to significantly improve birth weight, Maternal vitamin D levels and the extra supplementation of vitamin D during pregnancy significantly improved neonatal length and head circumference.
Databáze: OpenAIRE