Influence of Hydrolysis Susceptibility and Hydrophobicity of SN-38 Nano-Prodrugs on Their Anticancer Activity

Autor:	Liman Cong, Mayumi Takano-Kasuya, Farsai Taemaitree, Yoshitaka Koseki, Mika Watanabe, Hitoshi Kasai, Yoshikazu Ikuta, Keita Tanita, Tsunenobu Onodera, Hidetoshi Oikawa, Anh Thi Ngoc Dao, Takanori Ishida, Noriaki Ohuchi, Kohsuke Gonda, Hiroshi Tada
Rok vydání:	2019
Předmět:	010405 organic chemistry SN-38 General Chemistry Prodrug 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound Hydrolysis chemistry Nano Drug delivery Drug release
Zdroj:	Bulletin of the Chemical Society of Japan. 92:1305-1313
ISSN:	1348-0634 0009-2673
DOI:	10.1246/bcsj.20190088
Popis:	In the field of drug delivery, controllability of drug release site and duration are among the most important factors to manipulate the drug efficacy and side effects. In this paper, a series of na...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::788db4a201e521d9fd5ba7205e6ecd33 https://doi.org/10.1246/bcsj.20190088 Zobrazit plný text záznamu