Galenical formulations of amoxicillin/clavulanate and eradication of Helicobacter pylori in peptic ulcer patients
| Autor: | Boixeda D, L. De Rafael, C M de Argila, J. Sampedro, F. Baquero, Rafael Cantón |
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| Rok vydání: | 1993 |
| Předmět: |
Chemotherapy
medicine.medical_specialty Hepatology biology medicine.diagnostic_test medicine.drug_class business.industry medicine.medical_treatment Spirillaceae Antibiotics Gastroenterology Amoxicillin Helicobacter pylori biology.organism_classification digestive system diseases Internal medicine Biopsy medicine business Antrum Omeprazole medicine.drug |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 5:283-286 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/00042737-199304000-00015 |
| Popis: | Objective: To determine the efficiency of two amoxicillin/clavulanate galenical formulations (suspension and capsules) in the eradication of Helicobacter pylori in peptic ulcer patients. Design: Two groups of patients suffering from peptic ulcer and with positive antrum and corpus culture for H. pylori were treated with: (1) amoxicillin/clavulanate capsules and (2) amoxicillin/clavulanate suspension. The dosage in both groups was 500/125 mg orally every 8 h for 21 days. Omeprazole was also administered (40 mg/day for 30 days) in both groups. Follow-up visits were scheduled 8 days after antibiotic therapy and 3 months later. Methods: Thirty-nine adult patients with peptic ulcer disease diagnosed by endoscopy and with positive H. pylori culture in the biopsy specimens of gastric antrum and corpus were studied |
| Databáze: | OpenAIRE |
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