| Autor: |
Damien Ficheux, Céline Terrat, Thomas Trimaille, Bernard Verrier, Didier Gigmes |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
RSC Advances. 5:103060-103063 |
| ISSN: |
2046-2069 |
| DOI: |
10.1039/c5ra21578a |
| Popis: |
We report here a straightforward nanoprecipitation-based process to prepare functionalized polylactide (PLA) nanoparticles (NPs). It relies on an organic phase containing a PLA-based amphiphilic copolymer bearing N-succinimidyl esters that can spontaneously react with a peptide/protein located in the aqueous phase. The relevance of this strategy is supported by an improved antigenicity of immobilized HIV-1 Gag p24 protein. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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