Catalytic asymmetric synthesis of chiral thiohydantoins via the domino cyclization reaction of β,γ-unsaturated α-ketoesters and N,N′-dialkylthiourea
Autor: | Meng-Cheng Zhang, Dong-Chao Wang, Gui-Rong Qu, Hai-Ming Guo |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Organic Chemistry Frontiers. 9:4358-4364 |
ISSN: | 2052-4129 |
DOI: | 10.1039/d2qo00669c |
Popis: | The first catalytic asymmetric route to synthesize chiral thiohydantoins using a chiral phosphoric acid-catalyzed domino cyclization reaction of N,N′-dialkyl thioureas with β,γ-unsaturated α-ketoesters. |
Databáze: | OpenAIRE |
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