Catalytic asymmetric synthesis of chiral thiohydantoins via the domino cyclization reaction of β,γ-unsaturated α-ketoesters and N,N′-dialkylthiourea

Autor: Meng-Cheng Zhang, Dong-Chao Wang, Gui-Rong Qu, Hai-Ming Guo
Rok vydání: 2022
Předmět:
Zdroj: Organic Chemistry Frontiers. 9:4358-4364
ISSN: 2052-4129
DOI: 10.1039/d2qo00669c
Popis: The first catalytic asymmetric route to synthesize chiral thiohydantoins using a chiral phosphoric acid-catalyzed domino cyclization reaction of N,N′-dialkyl thioureas with β,γ-unsaturated α-ketoesters.
Databáze: OpenAIRE