Radiological properties of gold loaded soft tissue its application in nanoparticle enhanced X-ray therapy
| Autor: | K. Srinivasan, Nirmala grace, V. Poopathi, James Jabaseelan Samuel |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
010302 applied physics
Range (particle radiation) Materials science Attenuation chemistry.chemical_element Nanoparticle Soft tissue 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Bismuth Kerma chemistry 0103 physical sciences 0210 nano-technology Absorption (electromagnetic radiation) Platinum Biomedical engineering |
| Zdroj: | Materials Today: Proceedings. 9:428-437 |
| ISSN: | 2214-7853 |
| Popis: | High Z metal based nanoparticle such as gold, platinum and bismuth are used to enhance the therapeutic outcome in radiation oncology. In this current study, we assumed 7 and 18 mg/g of gold in ICRU-44 soft tissue and analytical models are used to calculate radiological properties. Our results suggest that optimum energy is 40 KeV for maximum dose enhancement factor; it was around 2.07, 3.76 for 7 and 18 mg/g Au respectively. Energy absorption build up factor of the gold loaded soft tissue is minimum compared to soft tissue alone. Kerma relative to air values was 1.05, 1.38 and 3.97 for soft tissue, 7mg and 18mg/g Au loaded soft tissue respectively. Mass energy absorption (µen/ϼ) and attenuation coefficients (µ/ϼ) are considerably increasing in the lower energy range up to 300 KeV compare to soft tissue alone and results are discussed. |
| Databáze: | OpenAIRE |
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