Pemphigus Vegetans of Neumann Type on Lip: A Case Report
| Autor: | Anil P. Gosavi, Nitika S. Deshmukh, Jheel Shriniwas Ambike, Ravindranath Brahmadeo Chavan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
030203 arthritis & rheumatology
Autoimmune disease medicine.medical_specialty integumentary system business.industry Acantholysis Pemphigus vulgaris Autoantibody Dermatology medicine.disease Desmoglein 030207 dermatology & venereal diseases 03 medical and health sciences Pemphigus 0302 clinical medicine immune system diseases medicine Vesiculobullous disease skin and connective tissue diseases Pemphigus vegetans business |
| Zdroj: | Journal of Skin and Stem Cell. 7 |
| ISSN: | 2423-7086 |
| DOI: | 10.5812/jssc.108089 |
| Popis: | Pemphigus is a chronic autoimmune vesiculobullous disease caused by autoantibodies directed against desmogleins (Dsgs). Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetative plaques, primarily occurring in flexures. It is a less common disease and involves the skin and mucosa due to disintegration of cellular adherence (acantholysis), resulting in intradermal split. We report this case of pemphigus vegetans of Neumann type for its rare presentation. We report a case of pemphigus vegetans, involving lips in a middle-aged female and sparing flexural areas. This patient was diagnosed on the basis of histopathology and treated successfully with intralesional steroids, resulting in the resolution of her plaques. |
| Databáze: | OpenAIRE |
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