Mesenchymal stem cell treatment of suspensory ligament branch desmitis: post mortem findings in a 10 year old Russion Warmblood gelding - a case report

Autor: D R Mountford, Roger Smith, Janet C. Patterson-Kane
Rok vydání: 2006
Předmět:
Zdroj: Pferdeheilkunde Equine Medicine. 22:559-563
ISSN: 0177-7726
DOI: 10.21836/pem20060506
Popis: Objective of the study was to compare the gross and histological appearance of one lateral suspensory ligament branch treated using autologous mesenchymal stem cells with one untreated lateral suspensory ligament branch in the same horse. Case records of a horse previously treated for lateral suspensory ligament branch desmitis using autologous mesenchymal stem cells were reviewed; the suspensory ligaments were dissected and the gross and histological findings recorded. Ultrasonographically, grossly, and histologically the treated suspensory ligament branch showed evidence of improved healing and formation of ligament-like tissue compared to the untreated suspensory branch in the contralateral limb. The implantation of cultured autologous mesenchymal stem cells into core suspensory branch lesions resulted in the formation of a matrix organisationally similar to normal suspensory ligament.
Databáze: OpenAIRE