| Popis: |
Hexadecylphosphocholine (INN: Miltefosine) is the prototype of a new class of antitumor phospholipids. Its specificially formulated solution (Miltex®) is an approved drug in Germany and has become a valuable tool in the treatment of cutaneous breast cancer and other malignant lesions (1). The systemic treatment with an oral miltefosine formulation was, however, relatively toxic to the GI-tract. Therefore, the drug could not be adequately dosed and in initial clinical studies the overall response rates remained low (2). |
