Serum homocysteine level in children with Juvenile Idiopathic Arthritis
| Autor: | Shahana A Rahman, Mohammed Mahbubul Islam, Mujammel Haque, Fakhrul Alam |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Serum homocysteine level medicine.medical_specialty Homocysteine business.industry Serum homocysteine Case-control study Arthritis Normal level General Medicine Homocysteine levels medicine.disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Internal medicine Medicine Juvenile 030212 general & internal medicine business |
| Zdroj: | Bangladesh Medical Research Council Bulletin. 46:12-16 |
| ISSN: | 2224-7238 0377-9238 |
| DOI: | 10.3329/bmrcb.v46i1.47463 |
| Popis: | Background: Juvenile Idiopathic Arthritis (JIA) is the most common chronic rheumatic disease of childhood and a leading cause of short and long-term disability. Abnormal level of serum homocysteine (Hcy) may be found in Juvenile idiopathic arthritis (JIA) patients. Some studies were done on serum homocyestine levels in children with JIA which showed conflicting results. So far, no study regarding the Hcy level in JIA patients was done in Bangladesh. Objectives: The study was aimed to assess the homocysteine level in children with different subtypes of JIA. Methods: It was a cross sectional and case control study. Fifty newly diagnosed cases of JIA attending the Pediatric Rheumatology clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from January 2016 to March 2017 were included. Fifty age and sex matched controls were selected. Serum homocysteine levels were measured in both cases and controls. Results: Among JIA patients, 36% had high serum homocysteine (Hcy) level whereas 100% of controls had normal level. Mean hcy level was significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|