Further accumulation of Cd in renal cellular membranes caused by administration of desferrioxamine to Cd-burdened rats
| Autor: | Kyoko Kon, Motoki Yonekawa, Kazutaka Kukita, Toshio Higa, Jun-ichi Sudo, Akio Kawamura, Jun Terui, Tadamasa Kon |
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| Rok vydání: | 1999 |
| Předmět: |
Nephrology
medicine.medical_specialty Cadmium Physiology business.industry medicine.medical_treatment chemistry.chemical_element Metal toxicity Pharmacology medicine.disease Nephrotoxicity Nephropathy chemistry Physiology (medical) Internal medicine medicine Metallothionein Chelation Hemodialysis business |
| Zdroj: | Clinical and Experimental Nephrology. 3:23-28 |
| ISSN: | 1437-7799 1342-1751 |
| Popis: | Background. Desferrioxamine (DFO) a chelating agent, is used to treat metal toxicity caused by iron and aluminum in patients on hemodialysis. We hypothesized that DFO could also be used to treat cadrium-induced nephropathy. Animal experiments were therefore performed to explore whether DFO removed cadmium (Cd) from the kidneys of rats with a Cd burden. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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