A two-step synthesis of new macrobicyclic aza-ligands starting from 'trans'dioxocyclam as diprotected macrocycle
Autor: | Stéphane Brandès, Franck Denat, Roger Guilard, Sylvie Lacour |
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Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 38:4417-4420 |
ISSN: | 0040-4039 |
DOI: | 10.1016/s0040-4039(97)00944-1 |
Popis: | A rapid and convenient synthesis of two small aza-cryptands containing a 1,4,8,11-tetraazacyclotetradecane backbone is reported. This strategy can be applied to the preparation of many other aza-cages by varying the nature of the cross linker. Moreover, the two remaining secondary amine sites may allow the functionalization of these ligands or their grafting on a polymer. |
Databáze: | OpenAIRE |
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