A two-step synthesis of new macrobicyclic aza-ligands starting from 'trans'dioxocyclam as diprotected macrocycle

Autor: Stéphane Brandès, Franck Denat, Roger Guilard, Sylvie Lacour
Rok vydání: 1997
Předmět:
Zdroj: Tetrahedron Letters. 38:4417-4420
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00944-1
Popis: A rapid and convenient synthesis of two small aza-cryptands containing a 1,4,8,11-tetraazacyclotetradecane backbone is reported. This strategy can be applied to the preparation of many other aza-cages by varying the nature of the cross linker. Moreover, the two remaining secondary amine sites may allow the functionalization of these ligands or their grafting on a polymer.
Databáze: OpenAIRE