Survival and adherence to cpap in the elderly
| Autor: | Muñoz Méndez J, Alonso-Moralejo R, M.J. Díaz de Atauri, Daniel López-Padilla, S. De La Torre Carazo, T. Díaz Cambriles |
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| Rok vydání: | 2013 |
| Předmět: |
Pediatrics
medicine.medical_specialty education.field_of_study business.industry medicine.medical_treatment Population General Medicine medicine.disease nervous system diseases respiratory tract diseases Obstructive sleep apnea Apnea–hypopnea index Cohort medicine Life expectancy Cpap treatment In patient Continuous positive airway pressure education business |
| Zdroj: | Sleep Medicine. 14:e25-e26 |
| ISSN: | 1389-9457 |
| DOI: | 10.1016/j.sleep.2013.11.023 |
| Popis: | Introduction The prevalence of Obstructive Sleep Apnea (OSA) increases with age, as well as life expectancy in years has extended in the past decades. Regarding OSA and elderly population, scientific publications tend to consider an elder person the one who is 65 or more years old. Whereas OSA has been related to cardiovascular and recently to cancer mortality, Continuous Positive Airway Pressure (CPAP) treatment has demonstrated reducing it in specific groups of population. The aim of our study was to analyze the survival in patients older than 80 years who adhered to CPAP treatment. Materials and methods A cohort of patients older than 80 years diagnosed of OSA during the period 2000–2010 at our Sleep Unit was followed. An Apnea Hypopnea Index (AHI) ⩾15 was considered diagnostic of OSA and ⩾30 of severe OSA. The use of at least 3.5 h/night was considered adherence to CPAP treatment. Log-rank and Kaplan Meier were used for statistical analysis. Results 122 patients older than 80 years were diagnosed of OSA during the mentioned period, of which 62 were men. With a mean age of 85.6 ± 2.6 years, an AHI 48.3 ± 21.6, a total of 53 deaths were documented. Unadjusted all-cause mortality was significantly increased in the group of patients which did not adhere to CPAP (a mean survival of 90 months, CI95% 67–113 in the no-adherence group vs. 127, CI95% 110–144 in the adherence group). This finding persisted when the subgroup with an AHI ⩾ 30 was analyzed (n = 94), where a significantly difference was found (76 months, CI95% 44–108 in the no-adherence group vs. 127, CI95% 110–144 in the adherence group). Conclusion It seems adherence to CPAP is related to an increased survival in patients older than 80 years old diagnosed of OSA, not only in the entire group but also in the subgroup with severe OSA. Acknowledgements No conflict of interests took place during the follow up of the presented cohort. |
| Databáze: | OpenAIRE |
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