Recent progress toward the total synthesis of humulanolides

Autor:	Chuang-Chuang Li, Xin Liu, Shao-Ping Li, Jing-Chun Han, Jing Zhao
Rok vydání:	2017
Předmět:	010405 organic chemistry Stereochemistry Chemistry Organic Chemistry Drug Discovery Total synthesis 010402 general chemistry Structural motif 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences
Zdroj:	Tetrahedron. 73:3289-3303
ISSN:	0040-4020
DOI:	10.1016/j.tet.2017.05.009
Popis:	The humulanolides are a series of sesquiterpene lactones, most of which have unique and challenging structure. The humulanolides have exhibited anticancer activity. The combinations of fascinating structural motifs and promising pharmacological properties have prompted significant interest in the synthetic community. In this review, we provide a summary of recent progress regarding the total synthesis of humulanolides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::77fa40a0491a570ba100496916b44630 https://doi.org/10.1016/j.tet.2017.05.009 Zobrazit plný text záznamu Full Text from ScienceDirect