Effect of remifentanil on oculocardiac reflex in paediatric strabismus surgery

Autor: Seok Reyol Choi, Seung Cheol Lee, Ji Hyeon Lee, J. M. Lee, Chan Jong Chung
Rok vydání: 2008
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 52:1273-1277
ISSN: 0001-5172
DOI: 10.1111/j.1399-6576.2008.01745.x
Popis: Background: Rapidly acting narcotics enhance the degree of bradycardia due to the oculocardiac reflex (OCR) elicited by extraocular muscle (EOM) tension during strabismus surgery. We evaluated and compared the effects of remifentanil and sevoflurane on OCR during paediatric strabismus surgery. Methods: One hundred and twenty children, 1–9 years old, undergoing elective strabismus surgery, were randomly assigned to receive sevoflurane or remifentanil. No anticholinergic prophylaxis was administered. Anaesthesia was induced using ketamine 1.0 mg/kg or midazolam 0.15 mg/kg with 66% N2O in O2. Laryngeal mask airways were placed with rocuronium 0.5 mg/kg. Anaesthesia was maintained with sevoflurane 2.0–3.0 vol% with 66% N2O in O2 or remifentanil 0.75 μg/kg over 1 min and followed by the continuous infusion of remifentanil 0.5 μg/kg/min with 66% N2O in O2. Heart rate (HR) and blood pressure (BP) were measured and compared. OCR was defined as a reduction in HR of >20% induced by traction of an EOM. Results: During anaesthesia, HR and BP were maintained at a lower level in the remifentanil group than in the sevoflurane group (each, P
Databáze: OpenAIRE