New Synthesis of 1,4 Benzodiazepine-2,5-diones by Means of HCL Gas Catalyst

Autor:	M. Boumzebra, Ph. Viallefont, H. Kasmi, A. Dahdouh, M. L. Roumestant, M. Akssira
Rok vydání:	1993
Předmět:	Benzodiazepine chemistry.chemical_compound Cyclopenol chemistry medicine.drug_class Organic Chemistry medicine Anthranilic acid Cyclopenin Combinatorial chemistry Derivative (chemistry) Catalysis
Zdroj:	Synthetic Communications. 23:2265-2272
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397919308013783
Popis:	A new synthesis of 1,4- benzodiazepinediones 4 , particularly 1,4-dihydro1H-1,4-benzodiazepine-2,5-dione, 4c key intermediate of metabolites cyclopenin 9 , cyclopenol 10 , cyclopeptine 11 and dehydrocyclopeptine 12 , was achieved by action of dry HCl gas in DMF on compound 3 prepared from anthranilic acid derivative 1 and amino ester 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::77f037559caba5acca40c1b68dfb5dc3 https://doi.org/10.1080/00397919308013783 Zobrazit plný text záznamu