Cavanine, a novel α-hydroxybisbenzylisoquinoline alkaloid from Sciadotenia toxifera (Krukoff and A. C. Smith)

Autor:	Lew B. Killmer, Mary D. Menachery, Alan J. Freyer, Richard J. Steinbeiser, Eric W. Stern
Rok vydání:	2000
Předmět:	Folk medicine biology Chemistry Stereochemistry Alkaloid Organic Chemistry Substituent Bisbenzylisoquinoline alkaloid biology.organism_classification Biochemistry Sciadotenia toxifera chemistry.chemical_compound South american Drug Discovery Menispermaceae Benzylisoquinoline
Zdroj:	Tetrahedron Letters. 41:2843-2846
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)00299-9
Popis:	Sciadotenia toxifera (Krukoff and A. C. Smith), a member of the South American Menispermaceae, has been used in folk medicine for the treatment of malaria and as an ingredient of curare. From the basic fraction of this bush-rope, a new bisbenzylisoquinoline alkaloid, cavanine, was isolated. The novel structure of cavanine (1), incorporating a rare α-hydroxyl substituent on one of the benzylisoquinoline moieties, was completely determined by spectroscopic methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::77b0ef05a227efa712b324e2e54fdfd9 https://doi.org/10.1016/s0040-4039(00)00299-9 Zobrazit plný text záznamu Full Text from ScienceDirect