Two New Antidepressant Steroidal Aglycones from Stephanotis mucronata
| Autor: | Yi-Ping Ye, Li-Juan Gao, Xiaoyu Li, Shu-Juan Hao, Shi-Fang Xu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pharmacology
biology Traditional medicine 010405 organic chemistry business.industry Stephanotis Plant Science General Medicine 010402 general chemistry biology.organism_classification 01 natural sciences 0104 chemical sciences Complementary and alternative medicine Drug Discovery Antidepressant Medicine business |
| Zdroj: | Natural Product Communications. 13:1934578X1801300 |
| ISSN: | 1555-9475 1934-578X |
| DOI: | 10.1177/1934578x1801300504 |
| Popis: | Two new C21 steroidal aglycones, 12- O-( N-methyl) anthraniloyl-deacylmetaplexigenin (1) and 12- O-tigloyl-20- O-tigloylsarcostin (2), were isolated from the hydrolyzed extract of the EtOAc soluble extract of the roots of Stephanotis mucronata. Their structures were determined on the basis of chemical evidence and extensive spectroscopic methods. The potential antidepressant activities of compounds 1 and 2 were evaluated in mice forced swimming test. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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