Processing of kinetic microarray signals
| Autor: | Martin Hegner, Thomas Braun, François Huber, Christoph Gerber, Murali Krishna Ghatkesar, Hans Peter Lang, Natalija Backmann |
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| Rok vydání: | 2007 |
| Předmět: |
Normalization (statistics)
Data consistency Microarray Computer science Metals and Alloys Analytical chemistry Condensed Matter Physics Kinetic energy Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Electrical and Electronic Engineering DNA microarray Curve alignment Instrumentation Algorithm |
| Zdroj: | Sensors and Actuators B: Chemical. 128:75-82 |
| ISSN: | 0925-4005 |
| Popis: | Measurement of kinetics using microarrays requires adapted experimental analysis for data evaluation and normalization. Here we present a new algorithm based on alignment of data, which solves inconsistencies of current normalization methods utilizing baseline correction. Our results show that this method leads to better data consistency and relative errors four times smaller on average. |
| Databáze: | OpenAIRE |
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