Relationships Between Infectious Virus, Hemagglutinin and Complement-Fixing Antigen of ECHO Virus, Type 19

Autor:	Herbert A. Wenner, Akinyele Fabiyi
Rok vydání:	1963
Předmět:	Infectivity Tissue culture Antigen Cell culture Virus type Biology Hemagglutinin Virology General Biochemistry Genetics and Molecular Biology Virus Infectious virus Microbiology
Zdroj:	Experimental Biology and Medicine. 113:81-85
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-113-28283
Popis:	SummaryThe CF antigen of ECHO 19 virus can be separated from the hemagglutinin and infectious virus particle. Although the 3 properties, based on sedimentation, indicated a close association, nevertheless, during virus multiplication each emerged at different periods. Infectivity and HA properties were labile to heat and UV irradiation; the CF was stable to both heat and UV. Absorption of infected TC fluid with human “O”erythrocytes removed more than 99% of infectious virus and hemagglutinin. The CF antigen was unaffected by absorption which indicated that the infectivity and HA were more closely combined than the CF. The available data suggested that the CF antigen is an integral part of the virus particle (non-infectious).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::777a6151b89f6115dcf6db3840620c4e https://doi.org/10.3181/00379727-113-28283 Zobrazit plný text záznamu