Entrapment of DFPase in titania coatings from a biomimetically derived method
| Autor: | Heidi Schreuder Gibson, Robert Stote, David Ziegler, Shaun F. Filocamo |
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| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Materials science Scanning electron microscope Mechanical Engineering Biomolecule Inorganic chemistry Oxide chemistry.chemical_element Polymer engineering.material Condensed Matter Physics Titanium oxide chemistry.chemical_compound chemistry Coating Chemical engineering Mechanics of Materials engineering General Materials Science Silicon oxide Titanium |
| Zdroj: | Journal of Materials Research. 26:1042-1051 |
| ISSN: | 2044-5326 0884-2914 |
| Popis: | Silicon oxide has been widely used to encapsulate biomolecules to preserve their activity in less than ideal environments. However, there are other inorganic oxides with inherent properties that would be advantageous in creating a multifunctional material. Titanium oxide exhibits properties that have applications in areas such as electronics, energy conversion, and decontamination. Herein is reported the formation of titania coatings fabricated on polymer beads using a biomimetic approach and characterized with scanning electron microscopy and energy dispersive x-ray spectroscopy. The approach involves the use of functionalized polymer beads, which initiate oxide formation from a water-soluble titanium complex. The method was used to encapsulate the enzyme diisopropylfluorophosphatase, in situ, within the oxide matrix under buffered aqueous conditions while retaining its enzymatic activity against diisopropylfluorophosphate. In addition, the biomimetically produced titania was shown to exhibit UV-assisted degradation activity against an ethidium bromide dye, upon liberation from the coating template. |
| Databáze: | OpenAIRE |
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