The MATRICS Consensus Cognitive Battery, Part 1: Test Selection, Reliability, and Validity
| Autor: | Terry E. Goldberg, Raquelle I. Mesholam-Gately, James M. Gold, Ellen Stover, Lyle E. Baade, Michael F. Green, Steven Zalcman, Daniel R. Weinberger, Susan M. Essock, Larry J. Seidman, M Deanna, Jonathan D. Cohen, Robert S. Kern, Alexander S. Young, Robert K. Heaton, Stephen R. Marder, Helena C. Kraemer, Keith H. Nuechterlein, Frederick J. Frese, Wayne S. Fenton, Richard S.E. Keefe |
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| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | American Journal of Psychiatry. 165:203-213 |
| ISSN: | 1535-7228 0002-953X |
| DOI: | 10.1176/appi.ajp.2007.07010042 |
| Popis: | Objective: The lack of an accepted standard for measuring cognitive change in schizophrenia has been a major obstacle to regulatory approval of cognition-enhancing treatments. A primary mandate of the National Institute of Mental Health’s Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative was to develop a consensus cognitive battery for clinical trials of cognition-enhancing treatments for schizophrenia through a broadly based scientific evaluation of measures. Method: The MATRICS Neurocognition Committee evaluated more than 90 tests in seven cognitive domains to identify the 36 most promising measures. A separate expert panel evaluated the degree to which each test met specific selection criteria. Twenty tests were selected as a beta battery. The beta battery was administered to 176 individuals with schizophrenia and readministered to 167 of them 4 weeks later so that the 20 tests could be compared directly. Results: The expert panel ratings are presented for th... |
| Databáze: | OpenAIRE |
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