SNP-detecting DNA technologies: Solving problems of applied biochemistry

Autor:	I. N. Krakhmaleva, N. N. Chernov, E. B. Stolyarova, A. B. Shevelev, N. I. Shakhovskaya, S. S. Shishkin, A. G. Plugov, V. G. Khomenkov, A. I. Knyazev
Rok vydání:	2005
Předmět:	Genetics Growth hormone receptor Negative association Biology Applied Microbiology and Biotechnology Biochemistry Molecular biology Loss of heterozygosity chemistry.chemical_compound Exon chemistry SNP Allele Gene DNA
Zdroj:	Applied Biochemistry and Microbiology. 41:264-268
ISSN:	1608-3024 0003-6838
DOI:	10.1007/s10438-005-0045-1
Popis:	The heterozygosity of CANP3, ACTN3, and GHR genes in specialized collections was studied using state-of-the-art DNA technologies for DNA analysis. A new dinucleotide deletion (AC) at the beginning of exon 21 was identified in five individuals with a heterozygous CANP3 gene. Analysis of polymorphism (1747 C → T) of the ACTN3 gene demonstrated a positive association of allele C with high muscular performance. Real-time PCR assay of SNP1630 (A → C) in the GHR gene suggested a putative negative association of allele C of this SNP with high muscular performance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7730e11ff6d2879744a23a76d95b35f0 https://doi.org/10.1007/s10438-005-0045-1 Zobrazit plný text záznamu