Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency

Autor: David Kodr, Erika Kužmová, Radek Pohl, Tomáš Kraus, Michal Hocek
Rok vydání: 2023
Předmět:
Zdroj: Chemical Science. 14:4059-4069
ISSN: 2041-6539
2041-6520
DOI: 10.1039/d2sc06718h
Popis: New lipid-linked 2′-deoxyribonucleoside triphosphates were synthesized and used for enzymatic construction of various lipid–oligonucleotide conjugates capable of efficient anchoring to plasma membranes.
Databáze: OpenAIRE