Multicenter Evaluation of an MIC-Based Aztreonam and Ceftazidime-Avibactam Broth Disk Elution Test
Autor: | Harley Harris, Lili Tao, Emily B. Jacobs, Yehudit Bergman, Ayomikun Adebayo, Tsigedera Tekle, Shawna Lewis, Ashley Dahlquist, Taylor C. Abbey, Eric Wenzler, Romney Humphries, Patricia J. Simner |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Clinical Microbiology. 61 |
ISSN: | 1098-660X 0095-1137 |
Popis: | Due to limited therapeutic options, there is a clinical need to assess the in vitro activity of the combination of aztreonam (ATM) and ceftazidime-avibactam (CZA) to guide the therapeutic management of multidrug-resistant (MDR) Gram-negative organism infections. We set out to develop a practical MIC-based broth disk elution (BDE) method to determine the in vitro activity of the combination ATM-CZA using readily available supplies and compare it to reference broth microdilution (BMD). |
Databáze: | OpenAIRE |
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