Multicenter Evaluation of an MIC-Based Aztreonam and Ceftazidime-Avibactam Broth Disk Elution Test

Autor: Harley Harris, Lili Tao, Emily B. Jacobs, Yehudit Bergman, Ayomikun Adebayo, Tsigedera Tekle, Shawna Lewis, Ashley Dahlquist, Taylor C. Abbey, Eric Wenzler, Romney Humphries, Patricia J. Simner
Rok vydání: 2023
Předmět:
Zdroj: Journal of Clinical Microbiology. 61
ISSN: 1098-660X
0095-1137
Popis: Due to limited therapeutic options, there is a clinical need to assess the in vitro activity of the combination of aztreonam (ATM) and ceftazidime-avibactam (CZA) to guide the therapeutic management of multidrug-resistant (MDR) Gram-negative organism infections. We set out to develop a practical MIC-based broth disk elution (BDE) method to determine the in vitro activity of the combination ATM-CZA using readily available supplies and compare it to reference broth microdilution (BMD).
Databáze: OpenAIRE