Synthesis of 2,1-Borazaroquinolines and 2,1-Borazaroisoquinolines from Vinyl­aminopyridines and Potassium Organotrifluoroborates by Microwave-Assisted Heating

Autor: Myriam Ciordia Jiménez, Andrés A. Trabanco, Aránzazu García, Chiara Pagliuca, Ana Isabel de Lucas, Leenaerts Joseph Elisabeth, Manuela Ariza Bueno, M. Rosa Sanchez Casado, Morgane Barriol, Frederik J. R. Rombouts, Martinez Lamenca Carolina
Rok vydání: 2015
Předmět:
Zdroj: European Journal of Organic Chemistry. 2015:5221-5229
ISSN: 1434-193X
DOI: 10.1002/ejoc.201500622
Popis: Azaborines are an emerging class of compounds with applications in medicinal chemistry and materials science. The synthesis of a wide variety of borazaronaphthalenes has been reported in the last decade. However, access to other borazaro derivatives has been limited. A new approach to synthesize 2,1-borazaroquinolines and 2,1-borazaroisoquinolines from (vinylamino)pyridines and potassium organotrifluoroborates using microwave-assisted heating is reported. A substituted diverse set of new azaborines has been synthesized by this method, providing the first access to a family of 2,1-borazaroquinolines and 2,1-borazaroisoquinolines.
Databáze: OpenAIRE