STC-15, an oral small molecule inhibitor of the RNA methyltransferase METTL3, inhibits tumour growth through activation of anti-cancer immune responses associated with increased interferon signalling, and synergises with T cell checkpoint blockade
Autor: | Y. Ofir-Rosenfeld, L. Vasiliauskaitė, C. Saunders, A. Sapetschnig, G. Tsagkogeorga, M. Albertella, M. Carkill, J. Self-Fordham, J.B. Holz, O. Rausch |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | European Journal of Cancer. 174:S123 |
ISSN: | 0959-8049 |
Databáze: | OpenAIRE |
Externí odkaz: |