Popis: |
Additional file 3: Supplementary Table S1. Linear ACCEPT gates used for the automated enumeration of CTCs and tdEVs. Supplementary Table S2. Univariable Cox regression analyses of CK+ and CK- CTCs and tdEVs after log transformation. Supplementary Table S3. Sensitivity, specificity and accuracy of ≥ 23% CTCs and ≥ 7% tdEVs, double positive for CK and HER2, as tests to predict the HER2 status of the tissue. The accuracy increases with the total CTCs and tdEVs detected (≥ 1, 5, 10, 20, 50, 100) at the cost of number of eligible patients to be assessed. |