Cytokine Levels during the Early Phase of the Endotoxin Fever
| Autor: | Stanislav Vybíral, Joachim Roth, J. Kamínková, Eugen Zeisberger, D. Pospíšilová, J. Dornand, Ladislav Janský |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Lipopolysaccharide
business.industry medicine.medical_treatment Experimental autoimmune encephalomyelitis chemical and pharmacologic phenomena hemic and immune systems Endogeny medicine.disease Set point chemistry.chemical_compound Cytokine chemistry Hypothalamus Immunology Viral meningitis medicine Early phase business |
| Zdroj: | Thermal Balance in Health and Disease ISBN: 9783034874311 |
| DOI: | 10.1007/978-3-0348-7429-8_48 |
| Popis: | Fever induced by lipopolysaccharide (LPS) causes release of endogenous pyrogens into circulation. Since cytokines have a capacity to induce fever, when injected peripherally or centrally, the view prevails that they act as endogenous pyrogens (8). It is presumed that cytokines acting directly or indirectly on the hypothalamus induce fever by elevating the thermoregulatory set point. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|