Myocardial Contrast Echocardiography Yields Best Accuracy Using Quantitative Analysis of Digital Data from Pulse Inversion Technique: Comparison with Second Harmonic Imaging and Harmonic Power Doppler During Simultaneous Dipyridamole Stress SPECT Studies
| Autor: | H. Von Bibra, U. Niklasson, A. Hansen, D. Bone, L. Eurenius |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.diagnostic_test
business.industry Pulse (signal processing) Contrast effect Ultrasound Second-harmonic imaging microscopy General Medicine Single-photon emission computed tomography Harmonics medicine Harmonic Medical imaging Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Zdroj: | European Heart Journal - Cardiovascular Imaging. 3:271-282 |
| ISSN: | 2047-2412 2047-2404 |
| Popis: | Aims: This prospective study assesses the (1) feasibility of quantifying ultrasound myocardial perfusion studies based on the densitometric analysis of digital data and the (2) comparison of pulse inversion, second harmonic and harmonic power Doppler modalities with SPECT. Methods and Results: Twenty-three patients with suspected ischaemic heart disease had i.v. injections of TcSestamibi and Optison during a dipyridamole stress test for echocardiography in pulse inversion, second harmonic and harmonic power Doppler mode. Analysis was (a) visual by scoring and (b) quantitative by densitometry of digital data for background subtracted myocardial opacification (a.u.) and normalized contrast effect (%). In the nine control patients, myocardial opacification at stress was greater (P0·002) than in the pathologic group (5·83·3 vs 2·62·5 a.u. in pulse inversion, 5·42·1 vs 2·41·8 in second harmonic and 7·13·7 vs 4·93·7 a.u. in harmonic power Doppler). In the pathologic group, normalized contrast effect decreased significantly during stress (23·718·8 to 11·310·8%, P |
| Databáze: | OpenAIRE |
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