Coexistent transthyretin amyloid cardiomyopathy and monoclonal gammopathy: Diagnostic challenges and prognostic implications
| Autor: | Shivali Malhotra, Katherine Lee Chuy, J. P. Gomez |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Oncology
medicine.medical_specialty biology Amyloid business.industry Cardiomyopathy Disease 030204 cardiovascular system & hematology medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences Transthyretin 0302 clinical medicine Cardiac amyloidosis Internal medicine biology.protein Medicine Radiology Nuclear Medicine and imaging Medical diagnosis Cardiology and Cardiovascular Medicine business Amyloid cardiomyopathy Multiple myeloma |
| Zdroj: | Journal of Nuclear Cardiology. 29:519-527 |
| ISSN: | 1532-6551 1071-3581 |
| Popis: | Establishing an accurate diagnosis of amyloid subtype in patients with coexistent cardiac amyloidosis and monoclonal gammopathy is crucial due to treatment and prognostic implications. Here, we discuss a case of coexistent diagnoses of transthyretin amyloid cardiomyopathy and smoldering multiple myeloma, highlighting the challenges associated with the possibility of several disease combinations and the limitations of diagnostic testing. In addition, the importance of clinical clues such as disease course and progression, patient preference, and multidisciplinary collaboration should not be discounted in the diagnostic and management approach of these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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