Therapeutic Silencing of ENaC Expression with a Pulmonary Epithelial RNAi Trigger Delivery Platform Durably Improves Clearance in a Large Animal Model of Muco-Obstructive Lung Disease

Autor:	B.F. Dickey, A. Nicholas, T. Pei, E.W. Bush, J.R. Sabater, X. Li, M.A. Mall, M.A. Salathe, B. Given, Z. Trilling, A. Glebocka, Steven M. Rowe
Rok vydání:	2020
Předmět:	Epithelial sodium channel business.industry RNA interference Cancer research Gene silencing Medicine business medicine.disease Obstructive lung disease Large animal
Zdroj:	D71. CYSTIC FIBROSIS AND DISORDERS OF MUCOCILIARY APPARATUS.
DOI:	10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7472
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::76bdb0c03bc54b3f7f88702e861e6c77 https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7472 Zobrazit plný text záznamu