| Autor: |
Fabio Ariel Guarnieri, Henning Menzel, Monika Michalzik, Stephanus Büttgenbach, Steffen Harling, Virginia C Ayala |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Journal of Physics: Conference Series. 90:012025 |
| ISSN: |
1742-6596 |
| DOI: |
10.1088/1742-6596/90/1/012025 |
| Popis: |
In this work we report on a novel miniaturized pH-sensitive hydrogel-valve for implementation in a microfluidic system. The control of fluid movement represents a critical parameter in the design of these systems. To date, actuation methods for the delivery of sample fluids, such as electromagnetic, piezoelectric or thermopneumatic, require high power consumption. Using a microfluidic valve based on a stimuli-responsive material no external power source is necessary. For this reason smart materials like hydrogels that respond to external stimuli such as the pH-value are qualified. The presented valve was produced using soft-lithographic methods and consists of biocompatible materials. The actuator was fabricated in-situ and the activation of the valve was produced by use of different pH-values. The first investigations were made using a pH 1- and a pH 13-solution successively in order to test the actuator principle. Different times of exposure were used to polymerize the hydrogel and as a result it was discovered that 16 minutes was the most adequate. These tests demonstrated the operation of the hydrogel-valve and its applicability in a microfluidic device. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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