Prevalence and Risk Factors for Hepatitis Delta Virus Transmission among HBsAg Positive Blood Donors in Brazzaville, Congo
| Autor: | Chaldam Jespère Mbani, Edwige Paola Louanga Nanitelamio, Sara R. Mbao-Bongo, Donatien Moukassa, Brunel Monic Angounda, Serge Oscar Mokono, Fabien Roch Niama, Boris S. Bakoua |
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| Rok vydání: | 2021 |
| Předmět: |
Hepatitis B virus
medicine.medical_specialty HBsAg Secondary education Virus transmission business.industry viruses HEPATITIS DELTA virus diseases biochemical phenomena metabolism and nutrition medicine.disease_cause Defective virus Multiple sexual partners Management of Technology and Innovation Internal medicine Medicine Hepatitis D virus business |
| Zdroj: | Journal of Biosciences and Medicines. :43-50 |
| ISSN: | 2327-509X 2327-5081 |
| Popis: | Background: Hepatitis D virus (HDV) is a defective virus that requires the presence of hepatitis B virus (HBV) for replication. It is a major cause of severe acute and chronic hepatitis B. The objective of this study was to determine the prevalence and risk factors of HDV in blood donors. Methods: This was a descriptive, cross-sectional study involving HBsAg-positive blood donors covering the period from July to December 2020. Testing for HDV RNA was performed by conventional two-step RT-PCR. Data were analysed using SPSS version 22 software. Result: Of 113 HBsAg positive samples included in the study 22 or 19.5% were HDV positive. The prevalence of HDV was higher in the age group 31 - 45 years (45.5%), in male donors (71.4%) and in donors with secondary education (50.0%). Furthermore, 55.4% belonged to the family donor category. A significant statistical difference was observed between HDV infection, tattoos, piercings and multiple sexual partners. Conclusion: This study shows a high prevalence of HDV among blood donors in Brazzaville. |
| Databáze: | OpenAIRE |
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