ALKALINE PHOSPHATASES IN VARIOUS TISSUES OF THE RAT DURING THE ALARM-REACTION

Autor:	Marc Herlant, Paola S. Timiras
Rok vydání:	1950
Předmět:	medicine.medical_specialty medicine.drug_class medicine.medical_treatment Phosphatase Acid phosphatase Biology Steroid hormone Endocrinology Estrogen Internal medicine medicine biology.protein Endocrine system Alkaline phosphatase Testosterone Hormone
Zdroj:	Endocrinology. 46:243-252
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-46-2-243
Popis:	In recent years chemical and cytochemical evidence has accumulated which indicates that hormones act by influencing enzymatic processes. The best established hormone-enzyme relationship is that which exists between acid and alkaline phosphatase and the steroid hormones. The relationship of various endocrine states to serum and prostatic phosphatase concentration was first reported by Huggins and Hodges (1941) and since extended by these investigators (Pazos and Huggins, 1945, Huggins and Russell, 1946). Serum and bone phosphatases were subsequently found to be affected by estrogen and testosterone administration (Buchwald and Hudson, 1944, 1945) as were the alkaline and acid phosphatase of the kidney, liver and intestine of the mouse and rat following castration or steroid hormone treatment (Kochakian and Flick, 1943, Kochakian and Fox, 1944, Kochakian, 1946, Tissieres, 1948). The uterine alkaline phosphatase content reportedly fluctuates during the reproductive cycle in mice and in primates (Atkinson and...
Databáze:	OpenAIRE
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