Magnetic signal evaluation and imaging of magnetic nanoparticles in brain phantom
| Autor: | Washino, Masaomi, Nomura, Kota, Yamauchi, Kazuki, Matsuda, Tetsuya, Susumu, Yasuaki, Seino, Satoshi, Nakagawa, Takashi, Sakane, Toshiyasu, Kiwa, Toshihiko, Tonooka, Shun |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| DOI: | 10.18416/ijmpi.2022.2203036 |
| Popis: | Magnetic Particle Imaging (MPI) is an imaging modality that directly detects the nonlinear response of magnetic nanoparticles (MNPs). Spatial encoding is realized by saturating the magnetic moment of MNPs most everywhere except in the special point called the field free reagion in which magnetic field vanishes. Recently, it has been shown that the sensitivity of MPI can be improved by using a field free line (FFL) in which the field free region formed as a line. We developed a MPI equipmemt with FFL using a neodymium magnet and an iron yoke, and magnetic particle imaging of a mouse brain phantom was successfully performed. In addition, we studied the magnetization response of MNPs in the brain and found that the magnetic response of magnetic moment to external magnetic field in the brain is different from that in buffer solution. International Journal on Magnetic Particle Imaging, Vol 8 No 1 Suppl 1 (2022) |
| Databáze: | OpenAIRE |
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