Autor:	S. S. Shishkin, N. V. Adnoral, L. B. Rebrov, S. M. Terekhov, T. B. Krokhina, Yu. I. Denisov-Nikol'skii, T. D. Smirnova, B. A. Bykov, V. G. Chernikov
Rok vydání:	2001
Předmět:	Hamster General Medicine Cycloheximide Biology General Biochemistry Genetics and Molecular Biology Cell biology chemistry.chemical_compound chemistry Cell culture Immunology medicine Myocyte Cytotoxic T cell Cytotoxicity Dexamethasone medicine.drug
Zdroj:	Bulletin of Experimental Biology and Medicine. 131:573-575
ISSN:	0007-4888
DOI:	10.1023/a:1012314921787
Popis:	Cultures of human and mammalian cells presenting 4 types of differentiation (normal human fibroblasts and myoblasts, human and Syrian hamster hepatoma cells, and mouse/mouse hybridoma cells) were used in a panel biotest system. This system allowed to evaluate the cytotoxic and stimulatory effect of bioactive compounds by determining the dose-effect relationships and some quantitative parameters including LD50. Examination of some biolactive compounds of different nature (sangviritrin, escin, deltostim, cycloheximide, dexamethasone) confirmed high efficacy of this biotest system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::76519c24a26e49eb99eba96c98c1afd1 https://doi.org/10.1023/a:1012314921787 Zobrazit plný text záznamu Full text from SpringerLink