| Autor: |
Yue Cao, Xin-Rui Liu, Hong-Mei Song, Shin-Tai Chong, Yu-He Cui, Qi Huang, Ming-Xin Yu, Yang Bai, Hai-Yang Xu, Gang Zhao |
| Rok vydání: |
2022 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-1576186/v1 |
| Popis: |
Objective: To identify which the combination of diffusion tensor imaging (DTI) and neurophysiological monitoring (NM) is reliable in the quantitative and predictive evaluation of spinal cord function. Methods: Data acquisition was collected in 12 patients who underwent spinal cord tumor surgery in our hospital. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) data of the regions of interest (ROIs) on DTI images were obtained. Preoperative NM and intraoperative neurophysiological monitoring (IONM) were performed. Patients were followed up 2 weeks later. European myelopathy score (EMS score) was recorded pre- and post-operatively. Correlation analysis was conducted to evaluate spinal cord function.Results: The average value of ADC in the two ROIs before operation was higher than that in the area without spinal cord compression (P=0.026), while the average value of FA was the opposite (p=0.018). Preoperative FA value significantly decreased in the fiber-interrupted group and the moderate-to-severe-damage group (PConclusion: For spinal cord tumor patients, the combination of preoperative DTI and NM could quantify the postoperative spinal cord function and predict the prognosis more comprehensively. Preoperative FA value is more valuable to reflect the postoperative subjective symptom, while preoperative SEP amplitude is more meaningful to predict the improvement degree of disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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