A Practical Preparation of Thiol Carboxylic Esters of 2-(Isoxazolyl) Acetic Acids

Autor: Jihchin Chung, Pesti Jaan A, Jianguo Yin
Rok vydání: 1999
Předmět:
Zdroj: Synthetic Communications. 29:3811-3820
ISSN: 1532-2432
0039-7911
DOI: 10.1080/00397919908086021
Popis: High yields of several thiolesters of 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetic acid are easily prepared from the corresponding oxoester by the reaction with trimethyl silylated mercaptan and aluminum chloride. The selection of mercaptans expands the previous scope of this synthetic method.
Databáze: OpenAIRE